vivaldi (Viral Variant Location and Diversity) is an R package for analyzing viral genomes using next generation DNA sequencing.

The standard input is a vcf file.

Installation from CRAN


Install development version from github

To get a bug fix or to use a feature from the development version, you can install the development version of vivaldi from GitHub.

# install.packages("devtools")

Authors: Marrisa Knoll, Katherine Johnson, Megan Hockman, Eric Borenstein, Mohammed Khalfan, Elodie Ghedin, David Gresham


If you use vivaldi in published research, please cite:

Roder, A. E., et al. “Optimized Quantification of Intrahost Viral Diversity in SARS-CoV-2 and Influenza Virus Sequence Data.” bioRxiv (2022): 2021-05 URL