CB2: CRISPR Pooled Screen Analysis using Beta-Binomial Test

Provides functions for hit gene identification and quantification of sgRNA (single-guided RNA) abundances for CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) pooled screen data analysis. Details are in Jeong et al. (2019) <doi:10.1101/gr.245571.118> and Baggerly et al. (2003) <doi:10.1093/bioinformatics/btg173>.

Version: 1.2.1
Depends: R (≥ 3.5.0)
Imports: Rcpp (≥ 0.12.16), metap, magrittr, dplyr, tibble, stringr, ggplot2, tidyr, glue, pheatmap
LinkingTo: Rcpp, RcppArmadillo
Suggests: testthat, knitr, rmarkdown
Published: 2019-05-16
Author: Hyun-Hwan Jeong [aut, cre]
Maintainer: Hyun-Hwan Jeong <hyun-hwan.jeong at bcm.edu>
License: MIT + file LICENSE
NeedsCompilation: yes
Materials: README
CRAN checks: CB2 results

Downloads:

Reference manual: CB2.pdf
Vignettes: CB2 Tutorial
Package source: CB2_1.2.1.tar.gz
Windows binaries: r-devel: CB2_1.2.1.zip, r-release: CB2_1.2.1.zip, r-oldrel: CB2_1.1.zip
OS X binaries: r-release: CB2_1.2.1.tgz, r-oldrel: CB2_1.2.1.tgz
Old sources: CB2 archive

Linking:

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